Search
Insomnia Clinical Trials
A listing of 67 Insomnia clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 67
There are currently 67 active clinical trials seeking participants for Insomnia research studies. The states with the highest number of trials for Insomnia participants are California, Florida, Texas and Ohio.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Research Study
Recruiting
Are you tired of living with chronic cough? Our research study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough.
You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you!
You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you!
Conditions:
Chronic Cough
Refractory or Unexplained Chronic Cough
Cough
Asthma
Sinusitis
Featured Trial
Type 2 Diabetes Clinical Trial
Recruiting
Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.
Conditions:
Type 2 Diabetes
Diabetes Mellitus Type 2 in Obese
Diabetes Type Two
Type 2 Diabetes Mellitus
Diabete Type 2
Featured Trial
Crohn's Disease Clinical Study
Recruiting
Help us study a potential new way to treat Crohn's disease. We are seeking adults living with Crohn's disease to join our latest clinical trial to help us learn more. Eligible participants will receive study-related treatment, assessments, and care at no cost. You will also receive reimbursement for travel while participating. Health insurance is not required to take part.
Conditions:
Crohn's Disease
Crohn Disease
Crohns Disease
Crohn's Disease (CD)
Crohn Colitis
Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior
Recruiting
This study will test the effectiveness of a sleep-related primary suicide prevention program entitled TAILOR (Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior), which includes specific behavior-change strategies for adolescents at risk of suicidal behavior who suffer from difficulties falling asleep, staying asleep, and/or insufficient sleep.
Gender:
ALL
Ages:
Between 11 years and 18 years
Trial Updated:
03/18/2025
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: Insomnia, Suicidal Ideation, Suicide, Attempted
Enhancing Hypnotic Medication Discontinuation in Primary Care
Recruiting
Many individuals with insomnia seek treatment in primary care settings, where they often receive prescription hypnotic medications as their first and sometimes only treatment. However, extended use of these medications can lead to reliance and increased health risks, such as falls and cognitive impairments. While evidence-based approaches like physician-supervised medication tapering exist, they're not widely available in primary care.
Most primary care providers are willing to explore non-drug... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
06/03/2025
Locations: National Jewish Health, Denver, Colorado
Conditions: Insomnia, Hypnotic Dependence
Dose-finding Study Assessing the Efficacy, Safety, and Pharmacokinetics of Daridorexant in Subjects Aged 10 to < 18 Years With Insomnia Disorder
Recruiting
This study assesses the efficacy, safety, and pharmacokinetics of multiple-dose oral administration of daridorexant in pediatric subjects aged 10 to \< 18 years with insomnia disorder.
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
06/02/2025
Locations: Banner - University Medical Center Tucson, Tucson, Arizona +49 locations
Conditions: Insomnia
Digital CBT for Insomnia and Depression
Recruiting
This study has two primary objectives, each of which addresses critical clinical and research gaps for individuals who have co-occurring insomnia and depression. The first objective is to address whether sequential treatment of insomnia and depression is superior to a single treatment for either depression or for insomnia, and if so, which treatment sequence is optimal. The second objective is to determine if there are heterogeneity of treatment effects; that is, variation in which interventions... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/02/2025
Locations: University of Rochester Sleep Research Laboratory, Rochester, New York
Conditions: Depression, Insomnia
Pimavanserin for Insomnia in Veterans With PTSD
Recruiting
This is a preliminary randomized, double-blind, placebo-controlled trial comparing pimavanserin 34mg at bedtime vs. placebo for the treatment of insomnia associated with post-traumatic stress disorder.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
05/29/2025
Locations: Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas
Conditions: Post-traumatic Stress Disorder, Insomnia
Implementation & Dissemination of a Digital Health Intervention for Adolescent Sleep
Recruiting
The goal of this study is to form a Teen Advisory Board (TAB), who will partner with our study team to co-design a beta-test a new prototype of the Firefly program, a mobile-native insomnia cognitive behavioral therapy intervention for teens. This new prototype will have addressed issues that adolescents who had used the first version of the program deemed to be barriers to engaging with the treatment.
Gender:
ALL
Ages:
Between 13 years and 18 years
Trial Updated:
05/28/2025
Locations: Kansas University Medical Center, Kansas City, Kansas
Conditions: Insomnia, Adolescent, Digital Health
Move and Snooze: Adding Insomnia Treatment to an Exercise Program to Improve Pain Outcomes in Older Adults With Knee Osteoarthritis
Recruiting
This research will compare the effectiveness of a remotely delivered personalized exercise coaching plus an evidence-based sleep improvement intervention to remotely delivered personalized exercise coaching alone for knee osteoarthritis pain.
The study team hypothesize that the combined intervention will result in greater improvements in patient-reported pain intensity, recorded with real-time data capture, than remotely delivered exercise coaching alone.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
05/14/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Knee Osteoarthritis, Insomnia
Sleep Mechanisms Of Regulating Emotions
Recruiting
This project is the second phase of a two-phased project investigating the impact of a proven sleep intervention, Cognitive Behavioral Therapy for Insomnia (CBT-I) on engagement of the emotion regulation brain network as a putative mechanistic target.
Gender:
ALL
Ages:
Between 25 years and 60 years
Trial Updated:
05/07/2025
Locations: Stanford University, Palo Alto, California
Conditions: Insomnia, Depression
Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients
Recruiting
The Sleep Optimization for Brain Health Outcomes in Older Surgical Patients (SLEEP-BOOST) is a pilot randomized, controlled, singled-blinded (participant) trial in major orthopedic joint surgery patients that will build on a previously clinically tested cognitive behavioral therapy for insomnia (CBT-I) mobile application paired with a wearable device (wrist actigraphy).
Gender:
ALL
Ages:
65 years and above
Trial Updated:
05/05/2025
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Insomnia, Postoperative Delirium, Delayed Neurocognitive Recovery, Postoperative Neurocognitive Disorder
Sleep Treatment Education Program for Cancer Survivors: STEP-Together
Recruiting
This single-arm research study of off-treatment cancer survivors with self-reported symptoms of insomnia will test the Sleep Treatment Education Program Together (STEP-Together) intervention which is delivered as a synchronous group session by videoconference.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/05/2025
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Insomnia, Insomnia Chronic, Survivorship
Adapting CBT-I for Hazardous Alcohol Users
Recruiting
The goal of this intervention development trial is to develop, refine, and test a telephone-delivered, 4-session version of cognitive behavioral therapy for insomnia adapted to hazardous alcohol users with co-occurring insomnia. The project will begin with a small, open label pilot to refine the intervention and proceed to a small, randomized trial comparing the intervention to a sleep and alcohol education control condition.
The two main questions it aims to answer are whether the intervention... Read More
Gender:
ALL
Ages:
Between 25 years and 64 years
Trial Updated:
05/02/2025
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Insomnia, Harmful; Use, Alcohol
Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia
Recruiting
Individuals who have insomnia with short sleep duration (ISS) differ from individuals who have insomnia with normal sleep duration (INS) in terms of health risks (i.e., hypertension) and treatment response. This study will examine whether patients with ISS and INS demonstrate a differential response to two common insomnia treatments. One is behavioral, Cognitive Behavioral Therapy for Insomnia (CBT-I). The other is a widely prescribed, non-habit-forming medication, trazodone used at a low dose.... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/29/2025
Locations: National Jewish Health, Denver, Colorado +3 locations
Conditions: Insomnia, Insomnia Chronic, Insomnia, Primary, Blood Pressure, Blood Pressure, High
1 - 12 of 67